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50. "Annuale," SNL, 2008


Most women we know find the idea of a once-a-season menstrual cycle creepier than Joe Francis coming at them with a camera. Unlike boob jobs, waxing and diet pills, that shit just doesn't seem natural, and the Annuale sketch shows that even a big-pharma, pink-tinged ad campaign can't dispel that. Plus: Kristen Wiig moves one step closer to goddess-hood by making out with a dog. Take that, Vanity Fair.